Accueil > Term: Bateman function
Bateman function
Equation expressing the build up and decay in concentration of a substance (usually in plasma) based on first order uptake and elimination in a one compartment model, having the form
C = (ƒDκa/V(κa - κe))(exp(-κet) - exp(-κat))
where C is the concentration and D the dose of the substance, ƒ the fraction absorbed, and V the volume of distribution. κa and κe are the first order rate constants of uptake and elimination, respectively, and t is time.
- Partie du discours : noun
- Secteur d’activité/Domaine : Biologie; Chimie
- Catégorie : Toxicologie
- Company: National Library of Medicine
0
Créateur
- Walter Lane
- 100% positive feedback