HTC One is a series of Android smartphones designed and manufactured by HTC. All products in the One series were designed to be touchscreen-based and slate-sized, and run the Android mobile operating system (Android 4.0 Ice Cream Sandwich or subsequent Android releases) with the HTC Sense graphical user interface.

From 2010 to 2013, all HTC products starting from the HTC Sensation XE to the HTC One Mini were equipped with a Beats Audio equalizer. Later HTC devices beginning with the HTC One Max no longer ship with Beats Audio following the buyback of HTC's stake in Beats Electronics.